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The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm

1. The vasoactive peptide endothelin (ET) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid haemorrhage. In these studies we investigated the involvement of protein kinase C (PKC) in sustained vasoconstriction induced by ET-1 in canine cerebral arteries. We also ex...

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Autori principali: Wickman, Grant, Nessim, Mourad A, Cook, David A, Vollrath, Bozena
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572750/
https://ncbi.nlm.nih.gov/pubmed/11325788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704025
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