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Allosteric modulation of [(3)H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain

1. Binding of D,L-(E)-2-amino-4-[(3)H]-propyl-5-phosphono-3-pentenoic acid ([(3)H]-CGP39653), a selective antagonist at the glutamate site of the NMDA receptor, is modulated by glycine in rat brain tissue. We have further investigated this phenomenon in rodent and human brain by means of receptor bi...

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Autors principals: Mugnaini, Manolo, Meoni, Paolo, Bunnemann, Bernd, Corsi, Mauro, Bowery, Norman G
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572734/
https://ncbi.nlm.nih.gov/pubmed/11309261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704017
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