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Allosteric modulation of [(3)H]-CGP39653 binding through the glycine site of the NMDA receptor: further studies in rat and human brain

1. Binding of D,L-(E)-2-amino-4-[(3)H]-propyl-5-phosphono-3-pentenoic acid ([(3)H]-CGP39653), a selective antagonist at the glutamate site of the NMDA receptor, is modulated by glycine in rat brain tissue. We have further investigated this phenomenon in rodent and human brain by means of receptor bi...

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Detalhes bibliográficos
Main Authors: Mugnaini, Manolo, Meoni, Paolo, Bunnemann, Bernd, Corsi, Mauro, Bowery, Norman G
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572734/
https://ncbi.nlm.nih.gov/pubmed/11309261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704017
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