Pharmacological differences between the human and rat vanilloid receptor 1 (VR1)

1. Vanilloid receptors (VR1) were cloned from human and rat dorsal root ganglion libraries and expressed in Xenopus oocytes or Chinese Hamster Ovary (CHO) cells. 2. Both rat and human VR1 formed ligand gated channels that were activated by capsaicin with similar EC(50) values. Capsaicin had a lower...

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Detalhes bibliográficos
Main Authors: McIntyre, Peter, McLatchie, Linda M, Chambers, Anne, Phillips, Elsa, Clarke, Melanie, Savidge, Jonathan, Toms, Christy, Peacock, Marcus, Shah, Kirti, Winter, Janet, Weerasakera, Natasha, Webb, Mike, Rang, Humphrey P, Bevan, Stuart, James, Iain F
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572656/
https://ncbi.nlm.nih.gov/pubmed/11226139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703918
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