Pharmacological differences between the human and rat vanilloid receptor 1 (VR1)

1. Vanilloid receptors (VR1) were cloned from human and rat dorsal root ganglion libraries and expressed in Xenopus oocytes or Chinese Hamster Ovary (CHO) cells. 2. Both rat and human VR1 formed ligand gated channels that were activated by capsaicin with similar EC(50) values. Capsaicin had a lower...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McIntyre, Peter, McLatchie, Linda M, Chambers, Anne, Phillips, Elsa, Clarke, Melanie, Savidge, Jonathan, Toms, Christy, Peacock, Marcus, Shah, Kirti, Winter, Janet, Weerasakera, Natasha, Webb, Mike, Rang, Humphrey P, Bevan, Stuart, James, Iain F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572656/
https://ncbi.nlm.nih.gov/pubmed/11226139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703918
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