Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes

1. Mycophenolic acid (MPA) is primarily metabolized to a phenolic glucuronide (MPAG) as well as to two further minor metabolites: an acyl glucuronide (AcMPAG) and a phenolic glucoside (MPAG1s). This study presents investigations of the formation of these metabolites by human liver (HLM), kidney (HKM...

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Autori principali: Shipkova, M, Strassburg, C P, Braun, F, Streit, F, Gröne, H-J, Armstrong, V W, Tukey, R H, Oellerich, M, Wieland, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572641/
https://ncbi.nlm.nih.gov/pubmed/11226133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703898
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