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Black tea extract, thearubigin fraction, counteract the effects of botulinum neurotoxins in mice

Botulinum neurotoxin type A (BoNT/A, 1.5 nM) completely inhibited indirectly evoked twitches in in vitro mouse phrenic nerve-diaphragm preparations within 40 – 45 min. Black tea extract, thearubigin fraction (TRB), mixed with BoNT/A blocked the inhibitory effect of the toxin. The protective effect o...

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Detalhes bibliográficos
Main Authors: Satoh, Eiki, Ishii, Toshiaki, Shimizu, Yoshio, Sawamura, Shin-ichi, Nishimura, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572623/
https://ncbi.nlm.nih.gov/pubmed/11181419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703883
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