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Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

Heteromeric KCNQ5/Q3 channels were stably expressed in Chinese Hamster ovary cells and characterized using the whole cell voltage-clamp technique. KCNQ5/Q3 channels were activated by the novel anticonvulsant, retigabine (EC(50) 1.4 μM) by a mechanism that involved drug-induced, leftward shifts in th...

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Detalhes bibliográficos
Main Authors: Wickenden, Alan D, Zou, Anruo, Wagoner, P Kay, Jegla, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572592/
https://ncbi.nlm.nih.gov/pubmed/11159685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703861
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