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Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells
Heteromeric KCNQ5/Q3 channels were stably expressed in Chinese Hamster ovary cells and characterized using the whole cell voltage-clamp technique. KCNQ5/Q3 channels were activated by the novel anticonvulsant, retigabine (EC(50) 1.4 μM) by a mechanism that involved drug-induced, leftward shifts in th...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572592/ https://ncbi.nlm.nih.gov/pubmed/11159685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703861 |
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