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Differential modulation by GTPγS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [(3)H]-WAY100,635
1. The interaction of serotonergic ligands at human (h) 5-HT(1A) receptors expressed in Chinese hamster ovary cells was examined with the selective ‘neutral' 5-HT(1A) antagonist [(3)H]-WAY100,635. Its binding was saturable (K(D)=0.056 nM) with a B(max) (3.65 pmol mg(−1)) significantly higher th...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572578/ https://ncbi.nlm.nih.gov/pubmed/11159702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703832 |
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