Modification of adenosine modulation of synaptic transmission in the hippocampus of aged rats

1. We compared the modulation of synaptic transmission by adenosine A(1) receptors in the hippocampus of aged (24 months) and young adult rats (6 weeks). 2. The adenosine A(1) receptor agonist, N(6)-cyclopentyladenosine, was less potent (P<0.05) to inhibit synaptic transmission in aged (EC(50)=53...

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Detaylı Bibliyografya
Asıl Yazarlar: Sebastião, A M, Cunha, R A, de Mendonça, A, Ribeiro, J A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572495/
https://ncbi.nlm.nih.gov/pubmed/11139440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703736
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