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Modification of adenosine modulation of synaptic transmission in the hippocampus of aged rats

1. We compared the modulation of synaptic transmission by adenosine A(1) receptors in the hippocampus of aged (24 months) and young adult rats (6 weeks). 2. The adenosine A(1) receptor agonist, N(6)-cyclopentyladenosine, was less potent (P<0.05) to inhibit synaptic transmission in aged (EC(50)=53...

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Hlavní autoři: Sebastião, A M, Cunha, R A, de Mendonça, A, Ribeiro, J A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572495/
https://ncbi.nlm.nih.gov/pubmed/11139440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703736
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