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Differential vasoconstrictor activity of human urotensin-II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey

1. Urotensin-II (U-II) and its G-protein-coupled receptor, GPR14, are expressed within mammalian cardiac and peripheral vascular tissue and, as such, may regulate mammalian cardiovascular function. The present study details the vasoconstrictor profile of this cyclic undecapeptide in different vascul...

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Bibliographic Details
Main Authors: Douglas, Stephen A, Sulpizio, Anthony C, Piercy, Valerie, Sarau, Henry M, Ames, Robert S, Aiyar, Nambi V, Ohlstein, Eliot H, Willette, Robert N
Format: Artigo
Language:Inglês
Published: 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572453/
https://ncbi.nlm.nih.gov/pubmed/11090097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703690
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