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Endomorphin-1 induced desensitization and down-regulation of the recombinant μ-opioid receptor
1. Endomorphin-1 (E1) is a peptide with high affinity and selectivity for the μ-opioid receptor. The aim of this study was to determine if endomorphin-1 caused desensitization and down-regulation of the μ-opioid receptor expressed in Chinese hamster ovary cells. 2. Following 10 μM E1 pre-treatment,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572439/ https://ncbi.nlm.nih.gov/pubmed/11082131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703683 |
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