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The effects of endomorphin-1 and endomorphin-2 in CHO cells expressing recombinant μ-opioid receptors and SH-SY5Y cells

1. Endomorphin-1 and -2 (E-1/E-2) have been proposed as endogenous ligands for the μ-opioid receptor. The aims of this study are to characterize the binding of E-1/E-2 and the subsequent effects on cyclic AMP formation and [Ca(2+)](i) levels in SH-SY5Y and Chinese hamster ovary (CHO) cells expressin...

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Autores principales: Harrison, C, McNulty, S, Smart, D, Rowbotham, D J, Grandy, D K, Devi, L A, Lambert, D G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571641/
https://ncbi.nlm.nih.gov/pubmed/10510460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702798
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