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Inhibition of HERG1 K(+) channels by the novel second-generation antihistamine mizolastine
1. Ventricular arrhythmias are rare but life-threatening side effects of therapy with the second-generation H(1) receptor antagonists terfenadine and astemizole. Blockade of the K(+) channels encoded by the Human Ether-à-go-go-Related Gene 1 (HERG1) K(+) channels, which is the molecular basis of the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572425/ https://ncbi.nlm.nih.gov/pubmed/11082114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703654 |
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