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Differences in the effects of urinary incontinence agents S-oxybutynin and terodiline on cardiac K(+) currents and action potentials

1. The cardiac electrophysiological effects of S-oxybutynin, a single-enantiomer drug under evaluation for the management of urinary incontinence, have been investigated and compared with those of terodiline, an incontinence agent withdrawn following reports of QT lengthening and ventricular tachyar...

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Autori principali: Jones, Stephen E, Shuba, Lesya M, Zhabyeyev, Pavel, McCullough, John R, McDonald, Terence F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572333/
https://ncbi.nlm.nih.gov/pubmed/10991917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703595
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