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Barnidipine block of L-type Ca(2+) channel currents in rat ventricular cardiomyocytes
1. The effects of barnidipine and nifedipine on L-type Ca(2+) current (I(Ca(L))) were investigated in ventricular cardiomyocytes from rats. 2. Both barnidipine and nifedipine reduced I(Ca(L)) in a concentration and voltage dependent manner; the EC(50) were 80 and 130 nM at a holding potential of −80...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572272/ https://ncbi.nlm.nih.gov/pubmed/10952695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703514 |
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