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Failure of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) to inhibit soluble guanylyl cyclase in rat ventricular cardiomyocytes

1. The effects of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ), an inhibitor of soluble guanylyl cyclase (sGC), were investigated in aortic rings and ventricular cardiomyocytes from rats. The production of cyclic GMP was stimulated by NO(•)-donors or carbachol. Additionally, the effects of ODQ...

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Detalhes bibliográficos
Main Authors: Wegener, Jörg W, Closs, Ellen I, Förstermann, Ulrich, Nawrath, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566070/
https://ncbi.nlm.nih.gov/pubmed/10401560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702608
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