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Adrenomedullin inhibits spontaneous and bradykinin-induced but not oxytocin- or prostaglandin F(2α)-induced periodic contraction of rat uterus
In isolated rat uterine strips, adrenomedullin (AM) inhibited the spontaneous periodic contraction in a concentration-dependent manner (IC(50)=22.3±0.7 nM). The inhibitory effect of AM was prevented by either AM(22–52), a putative antagonist for AM receptors, or calcitonin gene-related peptide (CGRP...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572263/ https://ncbi.nlm.nih.gov/pubmed/10952659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703500 |
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