Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels

1. Long-term (⩾12 h) treatment of cultured bovine adrenal chromaffin cells with A23187 (a Ca(2+) ionophore) or thapsigargin (TG) [an inhibitor of sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA)] caused a time- and concentration-dependent reduction of cell surface [(3)H]-saxitoxin (STX) binding ca...

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Detalhes bibliográficos
Main Authors: Shiraishi, Seiji, Shibuya, Izumi, Uezono, Yasuhito, Yokoo, Hiroki, Toyohira, Yumiko, Yamamoto, Ryuichi, Yanagita, Toshihiko, Kobayashi, Hideyuki, Wada, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572695/
https://ncbi.nlm.nih.gov/pubmed/11264239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703960
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