Characterization of a novel VPAC(1) selective agonist and identification of the receptor domains implicated in the carboxyl-terminal peptide recognition

1. Vasoactive Intestinal Polypeptide (VIP) interacts with a high affinity to two subclasses of G protein coupled receptors named VPAC(1) and VPAC(2), and has a 3–10 fold preference for VPAC(1) over VPAC(2) receptors. Selective ligands for each receptor subclass were recently described. [R(16)]-PACAP...

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Main Authors: Van Rampelbergh, Jean, Juarranz, Maria-Guillerma, Perret, Jason, Bondue, Antoine, Solano, Rosa Maria, Delporte, Christine, De Neef, Philippe, Robberecht, Patrick, Waelbroeck, Magali
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572139/
https://ncbi.nlm.nih.gov/pubmed/10864888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703384
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