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Propylbenzilylcholine mustard is selective for rat heart muscarinic receptors having a low affinity for agonists.

Propylbenzilylcholine mustard (PrBCM), an irreversible muscarinic antagonist, inactivated receptors with a low affinity for agonists faster than those with a high affinity in rat heart membranes. This result was obtained using either: (a) a low ionic strength buffer (allowing heterogeneity among ant...

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Bibliographic Details
Main Authors: Christophe, J., De Neef, P., Robberecht, P., Waelbroeck, M.
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917101/
https://ncbi.nlm.nih.gov/pubmed/3708224
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