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Effect of pH on binding of agonists and antagonists to rat heart muscarinic receptors.

The pH-dependence of antagonist and agonist binding to rat heart muscarinic receptors was investigated at 25 degrees C, in the absence and in the presence of GTP. The small inhibitory effect observed at the lowest pH investigated (pH 6.0) on [N-methyl-3H]methscopolamine chloride and [methyl-3H]oxotr...

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Detalles Bibliográficos
Main Authors: Asselin, J, Waelbroeck, M, Robberecht, P, de Neef, P, Christophe, J
Formato: Artigo
Idioma:Inglês
Publicado: 1983
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152464/
https://ncbi.nlm.nih.gov/pubmed/6651771
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