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The effect of sulphydryl block on the binding of H1-antagonists to the muscarinic receptor.

The treatment of brain muscarinic receptors by p-chlormercuribenzoate is known to change structure-activity relationships for antagonists. The changes in binding affinity of H1-antagonists for this receptor have been measured; the changes are similar to those for intrinsic muscarinic antagonists.

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Detalhes bibliográficos
Main Authors: Burgen, A. S., Harbird, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045059/
https://ncbi.nlm.nih.gov/pubmed/6152826
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