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Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat
Responses to human urotensin-II (hU-II) were investigated in human and rat pulmonary arteries. Rat pulmonary arteries: hU-II was a potent vasoconstrictor of main pulmonary arteries (2–3 mm i.d.) (pEC(50), 8.55±0.08, n=21) and was ∼4 fold more potent than endothelin-1 [ET-1] (P<0.01), although its...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572074/ https://ncbi.nlm.nih.gov/pubmed/10807654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703314 |
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