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Role of L-arginine in the vascular actions and development of tolerance to nitroglycerin

1. The goal of this work was to test the role of nitric oxide synthase (NOS) and its substrate L-arginine in development of tolerance to nitroglycerin's (GTN) vasodilator actions. 2. GTN's effects on NOS activity and NO formation were tested in cultured bovine aortic endothelial cells (BAE...

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Detalhes bibliográficos
Main Authors: Abou-Mohamed, Gamal, Kaesemeyer, Wayne H, Caldwell, Ruth B, Caldwell, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572062/
https://ncbi.nlm.nih.gov/pubmed/10807657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703293
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