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Preservation of platelet responsiveness to nitroglycerine despite development of vascular nitrate tolerance

AIMS: Organic nitrates, via nitric oxide (NO) release, induce vasodilatation and inhibit platelet aggregation. Development of nitrate tolerance in some vascular preparations may be associated with diminished responsiveness to NO. To date it is not known to what extent vascular tolerance to organic n...

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Detalhes bibliográficos
Main Authors: Holmes, Andrew S, Chirkov, Yuliy Y, Willoughby, Scott R, Poropat, Susan, Pereira, Jeremy, Horowitz, John D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884829/
https://ncbi.nlm.nih.gov/pubmed/16187967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02437.x
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