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Role of clot-associated (-derived) thrombin in cell proliferation induced by fibrin clots in vitro

1. Thrombin is a potent mitogenic agent. Clot-associated thrombin retains its amidolytic and pro-aggregant activity. We therefore studied the ability of fibrin clots to induce proliferation in CCL39 cells (Chinese hamster lung fibroblasts), in the absence and presence of the thrombin inhibitors PPAC...

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Bibliografiska uppgifter
Huvudupphovsmän: Gandossi, E, Lunven, C, Berry, C N
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571920/
https://ncbi.nlm.nih.gov/pubmed/10696104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703137
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