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Role of clot-associated (-derived) thrombin in cell proliferation induced by fibrin clots in vitro
1. Thrombin is a potent mitogenic agent. Clot-associated thrombin retains its amidolytic and pro-aggregant activity. We therefore studied the ability of fibrin clots to induce proliferation in CCL39 cells (Chinese hamster lung fibroblasts), in the absence and presence of the thrombin inhibitors PPAC...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571920/ https://ncbi.nlm.nih.gov/pubmed/10696104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703137 |
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