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Role of clot-associated (-derived) thrombin in cell proliferation induced by fibrin clots in vitro

1. Thrombin is a potent mitogenic agent. Clot-associated thrombin retains its amidolytic and pro-aggregant activity. We therefore studied the ability of fibrin clots to induce proliferation in CCL39 cells (Chinese hamster lung fibroblasts), in the absence and presence of the thrombin inhibitors PPAC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gandossi, E, Lunven, C, Berry, C N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571920/
https://ncbi.nlm.nih.gov/pubmed/10696104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703137
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