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Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators known. This peptide is increased during migraine attacks and has been implicated in the pathogenesis of migraine headache. Here we report on the first small molecule selective CGRP antagonist: BIBN4096BS. In vit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571877/ https://ncbi.nlm.nih.gov/pubmed/10711339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703110 |
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