Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin-induced carotid haemodynamic changes in anaesthetised pigs

1. Calcitonin gene-related peptide (CGRP), a potent vasodilator released from capsaicin-sensitive trigeminal sensory nerves, seems to be involved in the pathogenesis of migraine. Hence, CGRP receptor antagonists may serve as a novel treatment for migraine. This study was therefore designed to invest...

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Detalhes bibliográficos
Main Authors: Kapoor, Kapil, Arulmani, Udayasankar, Heiligers, Jan P C, Garrelds, Ingrid M, Willems, Edwin W, Doods, Henri, Villalón, Carlos M, Saxena, Pramod R
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574043/
https://ncbi.nlm.nih.gov/pubmed/12970078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705451
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