Pharmacological characterization of antagonists of the C5a receptor

1. Potent and highly selective small molecule antagonists have recently been developed by us for C5a receptors (C5aR) on human polymorphonuclear leukocytes (PMN). In this study we compared a new cyclic antagonist, F-[OPdChaWR], with an acyclic derivative, MeFKPdChaWr, for their capacities to bind to...

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Autores principales: Paczkowski, Natalii J, Finch, Angela M, Whitmore, Jacqueline B, Short, Anna J, Wong, Allan K, Monk, Peter N, Cain, Stuart A, Fairlie, David P, Taylor, Stephen M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571783/
https://ncbi.nlm.nih.gov/pubmed/10602324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702938
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