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Pharmacological and electrophysiological characterization of novel NMDA receptor antagonists
This work reports the synthesis, and pharmacological and electrophysiological evaluation of new N-methyl-D-aspartic acid receptor (NMDAR) channel blocking antagonists featuring polycyclic scaffolds. Changes in the chemical structure modulate the potency and voltage dependence of inhibition. Two of t...
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| Yayımlandı: | ACS Chem Neurosci |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249113/ https://ncbi.nlm.nih.gov/pubmed/29767953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00154 |
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