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Histamine H(1)-receptor-mediated modulation of the delayed rectifier K(+) current in guinea-pig atrial cells: opposite effects on I(Ks) and I(Kr)

1. Histamine receptor-mediated modulation of the rapid and slow components of the delayed rectifier K(+) current (I(K)) was investigated in enzymatically-dissociated atrial cells of guinea-pigs using the whole cell configuration of the patch clamp technique. 2. Histamine at a concentration of 10 μM...

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Detalhes bibliográficos
Main Authors: Matsumoto, Yasunori, Ogura, Takehiko, Uemura, Hiroko, Saito, Toshihiro, Masuda, Yoshiaki, Nakaya, Haruaki
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571771/
https://ncbi.nlm.nih.gov/pubmed/10602335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702918
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