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Inhibitory effects of JTV-519, a novel cardioprotective drug, on potassium currents and experimental atrial fibrillation in guinea-pig hearts

1. We investigated the effects of JTV-519 (4-[3-(4-benzylpiperidin-1-yl)propionyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine monohydrochloride), a novel cardioprotective drug, on the repolarizing K(+) currents in guinea-pig atrial cells by use of patch-clamp techniques. We also evaluated the...

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Detalhes bibliográficos
Main Authors: Nakaya, Haruaki, Furusawa, Yoshie, Ogura, Takehiko, Tamagawa, Masaji, Uemura, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572470/
https://ncbi.nlm.nih.gov/pubmed/11090108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703713
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