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Bepridil differentially inhibits two delayed rectifier K(+) currents, I(Kr) and I(Ks), in guinea-pig ventricular myocytes

1. We investigated the effects of bepridil on the two components of the delayed rectifier K(+) current, i.e., the rapidly activating (I(Kr)) and the slowly activating (I(Ks)) currents using tight-seal whole-cell patch-clamp techniques in guinea-pig ventricular myocytes, under blockade of L-type Ca(2...

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Autori principali: Wang, Jin-Cheng, Kiyosue, Tatsuto, Kiriyama, Kuninori, Arita, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571802/
https://ncbi.nlm.nih.gov/pubmed/10588929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702959
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