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Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta

1. The sensitivity of the soluble guanylate cyclase (sGC)-cyclic guanosine-3′,5′-monophosphate (cyclic GMP) system to nitric oxide (NO) was investigated in mouse aorta from wild type (WT) and NO synthase (NOS) knockout (KO) animals. 2. The NO donor, spermine-NONOate (SPER-NO) was more potent in aort...

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Bibliographic Details
Main Authors: Hussain, Monira B, Hobbs, Adrian J, MacAllister, Raymond J
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571718/
https://ncbi.nlm.nih.gov/pubmed/10556946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702874
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