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Evidence for 5-HT(7) receptors mediating relaxation of human colonic circular smooth muscle
5-HT(4) receptors mediate relaxation of human colon circular muscle. However, after 5-HT(4) receptor blockade (SB 204070 10 nM), 5-HT still induced a relaxation (pEC(50) 6.3). 5-HT(4) receptors were sufficiently blocked, as the curves to 5-HT obtained in the presence of 10 and 100 nM SB 204070 were...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1999
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571702/ https://ncbi.nlm.nih.gov/pubmed/10556917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702762 |
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