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Pharmacological evidence for the 5-HT(7) receptor mediating smooth muscle relaxation in canine cerebral arteries

1. We investigated in the present study whether 5-HT is able to exert direct relaxant responses in canine basilar and middle cerebral arteries via the 5-HT(7) receptor. 2. In arterial rings deprived of endothelium and pre-contracted with prostaglandin F(2α) (2 μM), 5-HT, 5-carboxamidotryptamine (5-C...

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Detalhes bibliográficos
Main Authors: Terrón, José A, Falcón-Neri, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566051/
https://ncbi.nlm.nih.gov/pubmed/10401550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702580
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