Pharmacological characterization of 5-HT(4) receptors mediating relaxation of canine isolated rectum circular smooth muscle

1. This study aimed to characterize for the first time in vitro 5-HT(4) receptors in the canine gastrointestinal tract. For this purpose, we used circular muscle strips of the canine isolated rectum. 2. In the presence of methysergide (60 μM), 5-HT induced relaxation of methacholine (1 μM)-precontra...

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Détails bibliographiques
Auteurs principaux: Prins, N H, Van Haselen, J F W R, Lefebvre, R A, Briejer, M R, Akkermans, L M A, Schuurkes, J A J
Format: Artigo
Langue:Inglês
Publié: 1999
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760667/
https://ncbi.nlm.nih.gov/pubmed/10455293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702665
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