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Enhanced phenylephrine-induced rhythmic activity in the atherosclerotic mouse aorta via an increase in opening of K(Ca) channels: relation to K(v) channels and nitric oxide

1. Mice lacking the apolipoprotein E and low density lipoprotein receptor genes (E°×LDLR°) develop atherosclerosis. The aim of this study was to investigate changes in endothelium-dependent vasodilation and vasomotion in thoracic aortic rings of E°×LDLR° mice. 2. K(+)-induced contractions of the aor...

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Detalhes bibliográficos
Main Authors: Jiang, Jiahua, Thorén, Peter, Caligiuri, Giuseppina, Hansson, Göran K, Pernow, John
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571694/
https://ncbi.nlm.nih.gov/pubmed/10516643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702855
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