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Endothelial dysfunction in atherosclerotic mice: improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin
1. Mice lacking the apolipoprotein E and low density lipoprotein receptor genes (E°xLDLR°) develop atherosclerosis and endothelial dysfunction. The aim of this study was to characterize the roles of L-arginine and tetrahydrobiopterin (BH(4)) for endothelium-dependent relaxation and the changes in th...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572463/ https://ncbi.nlm.nih.gov/pubmed/11090096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703705 |
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