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Activity profiles of dalargin and its analogues in μ-, δ- and κ-opioid receptor selective bioassays

1. To elucidate the structural features ensuring action of [D-Ala2, Leu5]-enkephalyl-Arg (dalargin), a series of dalargin analogues were tested for their effectiveness in depressing electrically-evoked contractions of the guinea-pig myenteric plexus-longitudinal muscle preparations (μ- and κ-opioid...

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Detalhes bibliográficos
Main Authors: Pencheva, Nevena, Pospišek, Jan, Hauzerova, Linda, Barth, Tomislav, Milanov, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571668/
https://ncbi.nlm.nih.gov/pubmed/10516634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702825
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