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Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum

1. The effect of allosteric regulators on the binding affinity of a number of cannabinoid receptor ligands of varying efficacy in the rat cerebellum was investigated. 2. Radioligand ([(3)H]-SR141716A) competition curves were constructed in the presence or absence of sodium ions, magnesium ions and g...

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Hlavní autoři: Griffin, Graeme, Wray, Emma J, Martin, Billy R, Abood, Mary E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571656/
https://ncbi.nlm.nih.gov/pubmed/10516649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702806
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