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Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues

1. The activities of a number of side-chain analogues of delta-8-tetrahydrocannabinol (Δ(8)-THC) in rat cerebellar membrane preparations were tested. 2. The affinities of each compound for the CB(1) receptor were compared by their respective abilities to displace [(3)H]-SR141716A and their efficacie...

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Detalhes bibliográficos
Main Authors: Griffin, Graeme, Williams, Stephanie, Aung, Mie Mie, Razdan, Raj K, Martin, Billy R, Abood, Mary E
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572574/
https://ncbi.nlm.nih.gov/pubmed/11159703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703827
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