Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR

The cellular mechanisms underlying the physiological effects of the orexins are poorly understood. Therefore, the pharmacology of the recombinant human orexin receptors was studied using FLIPR. Intracellular calcium ([Ca(2+)](i)) was monitored in Chinese hamster ovary (CHO) cells stably expressing o...

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Detalhes bibliográficos
Main Authors: Smart, D, Jerman, J C, Brough, S J, Rushton, S L, Murdock, P R, Jewitt, F, Elshourbagy, N A, Ellis, C E, Middlemiss, D N, Brown, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Special Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571615/
https://ncbi.nlm.nih.gov/pubmed/10498827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702780
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