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Stereoselective interaction of thiopentone enantiomers with the GABA(A) receptor
1. As pharmacokinetic differences between the thiopentone enantiomers seem insufficient to explain the ∼2 fold greater potency for CNS effects of (−)-S- over (+)-R-thiopentone, this study was performed to determine any enantioselectivity of thiopentone at the GABA(A) receptor, the primary receptor f...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571590/ https://ncbi.nlm.nih.gov/pubmed/10498837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702744 |
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