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Pharmacokinetics of thiopentone enantiomers following intravenous injection or prolonged infusion of rac-thiopentone

Aims Thiopentone is administered as a racemate (rac-thiopentone) for induction of anaesthesia as well as for neurological and neurosurgical emergencies. The pharmacokinetics and pharmacodynamics of rac-thiopentone have been extensively studied but the component R-(+)- and S-(−)- enantiomers, until v...

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Autori principali: Cordato, D J, Gross, A S, Herkes, G K, Mather, L E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042768/
https://ncbi.nlm.nih.gov/pubmed/9146846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00567.x
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