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Stereoselective interaction between the R enantiomer of warfarin and cimetidine.

The stereoselectivity of the pharmacokinetic interaction between warfarin and cimetidine was investigated in eight healthy volunteers. The warfarin enantiomers were given separately as single doses (15 mg) alone and during chronic administration of cimetidine (1 g day-1). Cimetidine did not interact...

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Autors principals: Choonara, I A, Cholerton, S, Haynes, B P, Breckenridge, A M, Park, B K
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1400859/
https://ncbi.nlm.nih.gov/pubmed/2938614
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