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Sonic hedgehog: restricted expression and limb dysmorphologies

Sonic hedgehog, SHH, is required for patterning the limb. The array of skeletal elements that compose the hands and feet, and the ordered arrangement of these bones to form the pattern of fingers and toes are dependent on SHH. The mechanism of action of SHH in the limb is not fully understood; howev...

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Hlavní autoři: Hill, Robert E, Heaney, Simon JH, Lettice, Laura A
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571058/
https://ncbi.nlm.nih.gov/pubmed/12587915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00148.x
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