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Sonic hedgehog: restricted expression and limb dysmorphologies

Sonic hedgehog, SHH, is required for patterning the limb. The array of skeletal elements that compose the hands and feet, and the ordered arrangement of these bones to form the pattern of fingers and toes are dependent on SHH. The mechanism of action of SHH in the limb is not fully understood; howev...

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Detalhes bibliográficos
Main Authors: Hill, Robert E, Heaney, Simon JH, Lettice, Laura A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571058/
https://ncbi.nlm.nih.gov/pubmed/12587915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2003.00148.x
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